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If you are considering Radiesse and Eri2 for under-eye and cheek sagging in Gangnam Nonhyeon-dong and Sinsadong
If you have begun to notice a hollow feeling under your eyes in the mirror and feel that your cheeks have sagged more than before — that could be an early signal of facial contour aging.
As you pass the mid-30s, collagen reduction and weakening of the extracellular matrix (ECM) progress together, and sagging gradually becomes noticeable starting from the cheeks, eye area, and jawline. In particular, under-eye hollowing is often the first signal of cheek sagging being reflected upward in a cascading structure, making it easy to dismiss as simply "dark circles have appeared," but in reality, structural changes in the facial contour itself may have begun.
At this stage, two procedures are frequently mentioned: Radiesse (CaHA collagen booster) and Eri2 (Ellavi Lituo Fine, direct ECM supplementation). The two procedures differ fundamentally in their approach, and whether they should be selected or combined varies depending on skin condition and sagging type. This is why a direct diagnosis by a board-certified plastic surgeon who comprehensively examines the degree of sagging and hollowing, skin thickness, and whether fat has shifted is the starting point.
Results may vary depending on individual conditions.
How do Radiesse and Eri2 work differently on the under-eye and cheek areas?
The two procedures are grouped together as "collagen regeneration type," but their actual mechanisms of action differ. Let me first organize the key points in a comparison table below.
| Category | Radiesse | Eri2 (Ellavi Lituo Fine) |
|---|---|---|
| Main Components | CaHA (calcium hydroxyapatite) microparticles + CMC gel | hADM (human acellular allograft dermis)-based 50μm particles |
| Mechanism | ① CMC gel creates immediate volume → ② CaHA particles stimulate fibroblasts, inducing collagen and elastin | Direct ECM (extracellular matrix) supplementation to reconstruct skin structure |
| Main Application Areas | Cheeks, nasolabial folds, jawline and other areas requiring volume | Exclusively for thin and delicate areas such as under-eye |
| Result Perception | Immediate volume + collagen proliferation over time | Gradual recovery of skin density, elasticity, and hydration |
| Duration of Results | According to clinical data, average 12-18 months (longer than HA fillers) | Varies depending on individual skin condition |
Radiesse is characterized by its dual mechanism. The CMC gel immediately fills under-eye hollowing, while CaHA microparticles gradually stimulate fibroblasts during the resorption process in the body, inducing collagen and elastin production. It is mainly suitable for cases of cheek hollowing or nasolabial fold improvement.
Eri2 (Ellavi Lituo Fine) is a preparation made by preserving key ECM constituent materials such as collagen, elastin, and glycosaminoglycans (GAG) from acellular allograft dermis (ADM), working by reconstructing the skin structure itself. According to a Sports Khan report, Ellavi Lituo is distinguished from existing fillers in that it preserves key ECM materials in this way. With a 50μm particle size, it is designed to be suitable for thin and sensitive areas such as the under-eye, and is utilized for skin density, elasticity, under-eye wrinkles, and eye area improvement.
When the two procedures are combined, synergy can be expected as cheek volume recovery (Radiesse) and under-eye skin structure reconstruction (Eri2) occur together, but whether to combine them and the order depends on the current skin condition.
What changes when a plastic surgery perspective is added — Beutiful story clinic's approach
When selecting a collagen booster or ECM regeneration procedure, people often focus only on "which product is good." However, clinically, the more important question is "where and how has sagging started in my face right now?"
Under-eye hollowing and cheek sagging are structurally connected. Because cheek fat migrates downward, creating a shadow under the eyes in a cascading structure, simply filling only the under-eye locally may not naturally restore the overall contour. This is why analyzing the sagging angle, skin thickness, and whether cheek fat has shifted from a plastic surgical perspective first, then designing the procedure combination, is the way to achieve results that do not look artificial.
At Beutiful story clinic, which simultaneously considers skin procedures and a plastic surgery perspective, Chief Director Suh Bit-na, a board-certified plastic surgeon, directly diagnoses under-eye and cheek condition and designs procedure combinations through a 1:1 reservation system where only one person receives concentrated care per hour. This is a method of proposing customized beauty plans based on scientific evidence using patent-pending facial precision imaging equipment, going beyond simple visual diagnosis.
The diagnosis and design process proceeds as follows:
• Facial structure analysis: Use patent-pending precision imaging equipment to confirm under-eye, cheek, and jawline sagging angles and whether cheek fat has shifted • Skin thickness and elasticity evaluation: Determine which formulation is suitable for thin areas like the under-eye • Procedure combination design: Decide whether Radiesse alone, Eri2 alone, or combined, and plan the order • Exclusion of unnecessary procedures: Provide an honest plan by not recommending procedures not necessary for the current condition
Is my under-eye and cheek condition sufficient with Radiesse and Eri2?
It is important to first identify whether there is room for improvement with non-surgical regeneration procedures or whether surgical approaches should be considered together. Use the checklist below to gauge your current condition.
✔ Cases with possibility of approaching with non-surgical regeneration procedures
• Under-eye hollowing has begun, but skin sagging is still mild • Cheek sagging is noticeable, but cheek fat displacement is not pronounced • There is a feeling of decreased skin elasticity, but overall sagging is at an early-to-moderate level • The main concern is "reduced skin density" rather than wrinkles
⚠ Cases where surgical approach should be considered together
• Prominent or protruding under-eye fat is clearly noticeable • Cheek fat has significantly descended, with pronounced nasolabial fold and cheek boundaries • Skin sagging is significant enough that elasticity recovery alone would be difficult to improve • Already had experience with regeneration procedures, but duration of effect was short
According to relevant clinical data, when fat protrusion is severe or skin sagging is significant, collagen booster and ECM regeneration procedures alone have limitations, and in such cases, considering whether to combine surgical approaches is recommended. Considering the cascading structure where cheek sagging leads to under-eye hollowing, complex causes may require complex approaches.
Given the Nonhyeon-dong and Sinsadong location, those residing near Apgujeong, Cheongdam-dong, and Seocho-dong can also easily access the clinic, so we encourage you to directly check which stage of sagging your current condition corresponds to.
The starting point of slow aging, why this timing is important
Beutiful story clinic in Nonhyeon-dong draws up a slow aging plan tailored specifically to you, adhering to the principle of domestic and international equal pricing and honest consultation without recommending unnecessary procedures.
Collagen reduction begins in the mid-20s, but when entering the 30s, its speed noticeably accelerates, which is known clinically. If you intervene with appropriate regeneration procedures at the stage when cheek sagging has just begun, it may be more effective in slowing the cascading aging progression leading to under-eye hollowing. Conversely, if you start after sagging has sufficiently progressed, your options may become limited.
The late 30s are the stage just before facial contour aging becomes full-fledged. Understanding your current skin condition accurately and developing the habit of slow aging by approaching only with what is necessary in minimal amounts is the way to maintain a natural-looking face in the long term. We encourage you to directly check the plan that perfectly fits your current face with a board-certified plastic surgeon with 15 years of experience.
Things you must verify before Radiesse and Eri2 procedures
Q1. Is it more effective if Radiesse and Eri2 are suitable together?
The two procedures have different application areas and mechanisms, so synergy can be expected in combined cases. Radiesse handles cheek volume and collagen induction, while Eri2 handles under-eye ECM reconstruction. However, whether to combine them and the order varies depending on the current skin condition, so it is important to decide after diagnosis. Results may vary depending on individual conditions.
Q2. After under-eye Eri2 procedure, how long do bruising and swelling last?
Because the under-eye skin is thin and has many blood vessels, bruising and swelling can occur. Generally, bruising tends to subside within a few days to 1-2 weeks, but there is a difference depending on individual skin condition and procedure scope. It is recommended to schedule the procedure with plenty of time before important events, and it is good to have sufficient consultation with medical staff before the procedure.
Q3. If Radiesse is different from simple filler, when do you start to feel the effects?
With Radiesse, you can immediately feel volumization due to CMC gel right after the procedure. Subsequently, as CaHA microparticles induce collagen and elastin production, skin elasticity and density tend to gradually improve over 2-3 months. The fact that immediate volumization and long-term regeneration effects appear sequentially is the distinguishing point from simple HA fillers.
Q4. Why is it important to receive treatment from a board-certified plastic surgeon at a non-factory type clinic?
Under-eye and cheek sagging is not just a surface skin problem but a complex structural change involving fat location, sagging angle, and skin thickness. A board-certified plastic surgeon can analyze this from both dermatological and plastic surgical perspectives and design an appropriate procedure combination. The more an environment like 1:1 reservation guarantees sufficient diagnosis time, the higher the likelihood that a customized minimal intervention plan tailored to the individual is created.
Results may vary depending on individual conditions